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Grants Policy 


Information on our Grants Policy is contained in the following documents:

1.     Research Strategy

2.     Scientific Advisory Committee Constitution

3.     Conflicts of Interest Policy

4.     Use of Animals in Research

Wessex Medical Trust is a member of the Association of Medical Research Charities (AMRC). All AMRC members support the AMRC policy on the use of animals in research which can be found at  http://www.amrc.org.uk/publications/statement-on-the-use-of-animals-in-research

Current Grant Offers


The period for applications for up to two PhD Studentships for commencement in October 2020 has now closed. There are currently no grants being offered.


Recent Grants Awarded



Dr Ali Roghanian (supervisor)            £98,473

Faculy of Medicine

PhD Studentship

The role of FcgRIIb in alpha-synuclein toxicity and propagation through the brain in Parkinson’s Disease

Dr Matthew Loxham  (supervisor)     £100,000

Faculty of Medicine

PhD Studentship

Toxicity of Particulate Emissions from Braking Systems – A Potential Role in Idiopathic Pulmonary Fibrosis

Dr Matthew Rose-Zerilli (supervisor)   £50,000

Faculty of Medicine

PhD Studentship jointly funded with the Centre for Cancer Immunology Talent Fund

The  tumour  micro-­environment  as  a  determinant  of  antigen  presentation  and  immune   response  in  oesophageal  cancer.


Professor Tim Elliott (supervisor)         £48,000

Faculty of Medicine

PhD Studentship

Polymorphism in the ERAP1 gene and its relevance to the prognosis and treatment of Cervical Cancer.

Professor Richard Oreffo (supervisor)  £40,000

Faculty of Medicine

PhD studentship jointly funded with Rosetrees Trust

Identifying the skeletal stem cell for regeneration- harnessing single cell RNA Sequencing and 3D Biofabrication.

Professor Jane Lucas (supervisor)         £54,000

Faculty of Medicine

PhD Studentship funded jointly with NIHR BRC

Characterisation of Primary Ciliary Dyskinesia (PCD) Epithelial Responses to Non-Typeable Haemophilus influenzae Biofilm Infection.

Dr Cornelia Blume                                 £20,000



Faculty of Medicine

The role of cilia in respiratory viral infections: Does an abnormal cilia beat pattern promote infections in primary cilia dyskinesia (PCD), a rare inherited disease?

Investigating how the altered movement of cells lining the airways leads to more infections in children with Primary Cilia Dyskinesia (PCD)

Dr Ali Roghanian                                   £19,075


Faculty of Medicine

Generation of humanised mouse models for evaluation of biologics in vivo

Developing better experimental models to support the development of new cancer therapies

Dr Faisal Rezwan                                  £18,646


Faculty of Medicine

Integrating multiple -omics data to solve the childhood asthma pathogenesis puzzle.

Using data science methods to understand childhood asthma


Dr Dean Bryant                                    £19,000


Faculty of Medicine

Development and optimisation of single cell ATAC seq for the study of CLL B cell receptor signalling.

Development of new methods to study the packing of genes in single cells to help understand the development of blood cancer

Dr Kris Ostridge                                   £19,138


Faculty of Medicine

Detecting Eosinophilic Inflammation in COPD using Novel SPECT-CT Imaging

Developing new ways to take images of the human lung in order to assess new treatments for asthma.



Dr Matthias Baud  (supervisor)           £40,000

School of Chemistry

PhD Studentship jointly funded with Rosetrees Trust

Modulating Wnt Signalling in Cancer: Small Molecules Targeting β-catenin.

To design new drug molecules which will inhibit a protein, beta catenin, which plays an important role in several cancers such as colorectal cancer.

Dr David Tumbarello    (supervisor)               £80,000

Faculty of Natural and Environmental Sciences

PhD Studentship

Investigating the translocation of parkin to damaged mitochondria and the mechanisms of mitophagy.

Investigating means nof maintaining healthy cells by limiting the natural production of harmful products.

Dr Yihua Wang    (supervisor)                        £80,000

Faculty of Natural and Environmental Sciences

PhD Studentship

Functional analysis of Sodium/glucose cotransporter 1 (SGLT1), a potential therapeutic target for PTEN-inactive breast cancer.

Investigating how drugs can treat breast cancer by targetting the protein PTEN.

Dr Sam Thompson                          £20,000

School of Chemistry

Pepetidomimetic inhibitors of HER2 positive breast cancer.

A new approach to designing drugs to inhibit proteins that are important in cancer.

Dr Shreyasi Chatterjee                    £13,000

Institute for Life Sciences

Investigating the mechanisms of pathological tau-clearance in 3D induced pluripotent stem-cell (iPSC) models of Alzheimer’s disease.

Investigating the biological pathway of how the brain clears abnormal proteins in diseases such as Alzheimer'.

Dr Melissa Andrews                         £20,000

School of Biological Sciences

Optimising stem cells for neuronal replacement in the CNS.

Developing new methods to generate stem cells to treat conditions such as brain or spinal cord injury.

Dr Liku Tezera                                £19,950

Faculty of Medicine

Developing the 3-dimensional cellular model of Tuberculosis by integrating co-axial bioelectrospray,technology and stem cells.

TB is still a major global killer. This research will use engineering methods to create a 3D model to assist understanding of how the disease resides in humans and identify new drugs to combat it.

Dr Yihua Wang                               £20,000

Faculty of Natural and Environmental Sciences

Epithelial-mesenchymal transition (EMT) induced by RAS activation in alveolar Type II cells leads to idiopathic pulmonary fibrosis (IPF) or lung cancer invasion?

This project aims to identify molecular switches that dictate the ability of RAS, a common cancer gene,  to contribute to either lung cancer or pulmonary fibrosis


Dr Jane Collins (supervisor)

PhD Studentship jointly funded by Rosetrees Trust and British Lung Foundation

Dissecting the WISP signalling network in idiopathic pulmonary fibrosis

Dr Edward Rogers         £19,451

Institute for Life Sciences

Grant dedicated to the memory of Pamela Kimber, former Trustee and Patron

Quantifying neuronal changes during age-related hearing loss with polarisation-contrast imaging.

Dr Matthew Blunt         £20,000


Faculty of Medicine

Overcoming IL-4 mediated drug resistance in Chronic Lymphocytic Leukaemia

Dr Dario Carugo          £19,845

Faculty of Medicine

Ultrastem—an Ultrasonic Toolbox for on-demand Modulation of Stem Cell Fate

Dr Sandi Dheensa       £17,600

Faculty of Medicine

Using digital health to facilitate the clinical integration of whole-genome sequencing.



Professor Anne Bruton (supervisor) £40,000

PhD Studentship  jointly funded with British Lung Foundation

 Breathing pattern recording and analysis: a potential new biomarker for respiratory disease


Dr Simon Crabb (supervisor) £40,000

PhD Studentship jointly funded with The Urology Foundation

 Investigating interactions between vacuolar ATPase proton pumps and androgen receptor signalling in prostate cancer


Dr Emily Swindle (supervisor) £40,000      

PhD Studentship jointly funded with Rosetrees Trust

Development of a human tissue based model of the airway using cell sheet engineering


Dr Fernando Calahorro     £20,000

Centre for Biological Sciences         

A microfluidic assay for drug discovery in Autism spectrum disorders.

Developing tools to identify new ways to use drugs in treating Autism.

Dr Mariana Vargas-Caballero    £19,500

Centre for Biological Sciences

What are the mechanisms of synapse loss in early Alzheimer’s disease in human neurons?”

Exploring the mechanism of memory loss in early Alzheimer’s disease.

Dr Katrin Deinhardt      £19,000          

Centre for Biological Sciences      

Targeting TrkB turnover: Identification of the TrkB E3 ubiquitin ligase.    

Developing tools drug discovery in Autism spectrum disorders.        

Dr Emma Reeves        £20,000        

Faculty of Medicine                                                                

The impact of Ankylosing Spondylitis associated ERAP1 allotype combinations on HLA-B27 misfolding.

Improving understanding of the causes of the  autoimmune condition Ankylosing Spondylitis.

Mr Marc Bullock     £19,916

Faculty of Medicine                 

Identification and characterisation of deregulated long non-coding RNAs during colorectal cancer progression – interplay between tumour stroma and epithelium.

Investigation of a new biological mechanism that may underlie colorectal cancer progression.


Professor Eugene Healy  (supervisor)    £80,000

Faculty of Medicine

PhD Studentship

Factors within skin cancer which influence development of metastases.

Dr Edd James & Dr Laura Bourne    £30,000

Faculty of Medicine

Cervical Cancer Appeal Grant

The role of ERAP1 in Cervical carcinoma



Mr Jay Self & Professor Andrew Lotery (supervisors)  £40,000

PhD Studentship jointly funded with Gift of Sight


A study of the first transgenic mouse model of Infantile Nystagmus

Dr Nicholas Evans (supervisor) £40,000

PhD Studentship jointly funded with Rosetrees Trust

Engineering mechanical stem cell niches for wound healing. 

Dr Massimiliano Mellone    £20,000

Faculty of Medicine

The role of the DNA Damage Response (DDR) pathway in myofibroblast differentiation

Can manipulating the interaction between cancer cells and normal tissue alter the progression of the disease?

Dr Veronika Jenei  £20,000

Faculty of Medicine

Epidermal growth factor receptor – integrin crosstalk in the regulation of cancer progression.

Investigating a cellular pathway that enables cancer to invade and spread around the body.

Dr Charles Birts   £20,000

Faculty of Medicine

Metabolic regulation of the breast cancer biomarker Annexin A3.

Investigating whether cell metabolism influences cancer growth.  This may lead to improved cancer diagnosis and whether a patient is likely to have a severe form of the disease.


Dr Diego Gomez-Nicola  £20,000

Centre for Biological Sciences

Impact of inflammation on neurogenesis during Alzheimer´s disease: understanding and modulating the self-repairing mechanisms of the brain. 

Identifying and modulating the mechanisms of self-repair of the brain, with the potential to replace lost neurons during Alzheimer's disease.

Dr Matthew Rose-Zerilli  £20,000

Faculty of Medicine

Establishing single cell genetic techniques for the analysis of cancer by understanding intra-clonal heterogeneity in the b-cell leukaemia, Chronic Lymphocytic Leukaemia. 

Understanding why, in some patients with leukaemia, some cancer cells evade being treated which results in relapse.

Dr Seung Seo Lee    £20,000

Department of Chemistry

Specific Chemical Probes for the Ubiquitin System.

Developing chemicals that modify cellular events that cancer cells are dependent on: this has the potential to lead to creating new types of drugs to treat cancer.

Dr Sumeet Mahajan     £20,000

Institute for Life Sciences

Multimodal label-free imaging for studying and evaluating stem cell plasticity. 

A completely new way of looking at living cells in the laboratory that aims to visualise the growing potential of stem cells, particularly towards new bone formation to treat osteoporosis and fractures.










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